Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases

Terpene cyclases catalyze the formation of diverse hydrocarbon scaffolds found in terpenoids. Here, the authors report the cryptic function of class I terpene cyclases as aromatic prenyltransferases and the universality of this cryptic feature is confirmed using enzymes from different sources.

Bibliographic Details
Main Authors: Haibing He, Guangkai Bian, Corey J. Herbst-Gervasoni, Takahiro Mori, Stephen A. Shinsky, Anwei Hou, Xin Mu, Minjian Huang, Shu Cheng, Zixin Deng, David W. Christianson, Ikuro Abe, Tiangang Liu
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17642-2