Blood-testis barrier integrity depends on Pin1 expression in Sertoli cells

Abstract The conformation and function of a subset of serine and threonine-phosphorylated proteins are regulated by the prolyl isomerase Pin1 through isomerization of phosphorylated Ser/Thr-Pro bonds. Pin1 is intensely expressed in Sertoli cells, but its function in this post mitotic cell remains un...

Full description

Bibliographic Details
Main Authors: Rabia Islam, Heein Yoon, Bong-soo Kim, Han-sol Bae, Hye-rim Shin, Woo-Jin Kim, Won-joon Yoon, Yun-Sil Lee, Kyung Mi Woo, Jeong-Hwa Baek, Hyun-Mo Ryoo
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07229-1