The role of specific checkpoint-induced S-phase transcripts in resistance to replicative stress.

Checkpoint activation during S phase modulates transcription. In response to replication arrest, the fission yeast Cds1 checkpoint kinase maintains the normal S-phase transcriptional program by regulating MBF, the S-phase transcription factor. We show that similar regulation occurs in response to DN...

Full description

Bibliographic Details
Main Authors: Chaitali Dutta, Nicholas Rhind
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2735676?pdf=render