Synthesis of 1-[(Aryl)(3-amino-5-oxopyrazolidin-4-ylidene) methyl]-2-oxo-1,2-dihydroquinoline-3-carboxylic Acid Derivatives and Their Breast Anticancer Activity

Synthesis of 1-[(Aryl)(3-amino-5-oxopyrazolidin-4-ylidene) methyl]-2-oxo-1,2-dihydroquinoline-3-carboxylic Acid Derivatives and Their Breast Anticancer Activity

This research aimed to produce new 1-[(aryl)(3-amino-5-oxopyrazolidin-4-ylidene) methyl]-2-oxo-1,2-dihydroquinoline-3-carboxylic acid derivatives and check their anticancer effect against the breast cancer MCF-7 cell line. The 2-oxo-1,2-dihydroquinoline-3-carboxylic acid (<b>4</b>) compo...

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Bibliographic Details
Main Authors: Ahmed Gaber, Walaa F. Alsanie, Majid Alhomrani, Abdulhakeem S. Alamri, Ibrahim M. El-Deen, Moamen S. Refat
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Crystals
Subjects:
anticancer drugs
cell-cycle arrest
<sup>1</sup>H-NMR
quinolinone derivatives
Online Access:https://www.mdpi.com/2073-4352/11/5/571

Internet

https://www.mdpi.com/2073-4352/11/5/571

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