Origin and evolution of sulfadoxine resistant Plasmodium falciparum.

The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine (CQ) and pyrimethamine resistance originated in this region and eventually spread to other Asian countries and Africa. However, there is a dearth in understanding the ori...

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Main Authors: Sumiti Vinayak, Md Tauqeer Alam, Tonya Mixson-Hayden, Andrea M McCollum, Rithy Sem, Naman K Shah, Pharath Lim, Sinuon Muth, William O Rogers, Thierry Fandeur, John W Barnwell, Ananias A Escalante, Chansuda Wongsrichanalai, Frederick Ariey, Steven R Meshnick, Venkatachalam Udhayakumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20360965/?tool=EBI