When Three Isn’t a Crowd: A Digyny Concept for Treatment-Resistant, Near-Triploid Human Cancers

When Three Isn’t a Crowd: A Digyny Concept for Treatment-Resistant, Near-Triploid Human Cancers

Near-triploid human tumors are frequently resistant to radio/chemotherapy through mechanisms that are unclear. We recently reported a tight association of male tumor triploidy with XXY karyotypes based on a meta-analysis of 15 tumor cohorts extracted from the Mitelman database. Here we provide a con...

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Bibliographic Details
Main Authors: Kristine Salmina, Bogdan I. Gerashchenko, Michael Hausmann, Ninel M. Vainshelbaum, Pawel Zayakin, Juris Erenpreiss, Talivaldis Freivalds, Mark S. Cragg, Jekaterina Erenpreisa
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Genes
Subjects:
near-triploid cancer
radioresistance
chemoresistance
reprogramming
digyny
polynuclear cancer cells
tripolar mitosis
pedogamy
tumor blastomeres
Online Access:https://www.mdpi.com/2073-4425/10/7/551

Internet

https://www.mdpi.com/2073-4425/10/7/551

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