Cytokine Profiling in Myeloproliferative Neoplasms: Overview on Phenotype Correlation, Outcome Prediction, and Role of Genetic Variants

Cytokine Profiling in Myeloproliferative Neoplasms: Overview on Phenotype Correlation, Outcome Prediction, and Role of Genetic Variants

Among hematologic malignancies, the classic Philadelphia-negative chronic myeloproliferative neoplasms (MPNs) are considered a model of inflammation-related cancer development. In this context, the use of immune-modulating agents has recently expanded the MPN therapeutic scenario. Cytokines are key...

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Bibliographic Details
Main Authors: Elena Masselli, Giulia Pozzi, Giuliana Gobbi, Stefania Merighi, Stefania Gessi, Marco Vitale, Cecilia Carubbi
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
myeloproliferative neoplasms
inflammation
cytokines
megakaryocytes
mutations
polymorphisms
Online Access:https://www.mdpi.com/2073-4409/9/9/2136

Internet

https://www.mdpi.com/2073-4409/9/9/2136

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