Mutational concordance analysis provides supportive information for double cancer diagnosis

Mutational concordance analysis provides supportive information for double cancer diagnosis

Abstract Background Mutation analysis using next-generation sequencing highlights the features of tumors with somatic alterations. However, the mutation profile of double cancer remains unclear. Here, we analyzed tumors derived from the same patient using whole exome sequencing (WES) to investigate...

Full description

Bibliographic Details
Main Authors: Keiichi Hatakeyama, Takeshi Nagashima, Akifumi Notsu, Keiichi Ohshima, Sumiko Ohnami, Shumpei Ohnami, Yuji Shimoda, Akane Naruoka, Koji Maruyama, Akira Iizuka, Tadashi Ashizawa, Hirotsugu Kenmotsu, Tohru Mochizuki, Kenichi Urakami, Yasuto Akiyama, Ken Yamaguchi
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Cancer
Subjects:
Whole exome sequencing
Double cancer
Tumor mutational burden
Poisson distribution
Online Access:https://doi.org/10.1186/s12885-021-07899-1

Internet

https://doi.org/10.1186/s12885-021-07899-1

Similar Items