Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01.

Viral infections can affect the glycosylation pattern of glycoproteins involved in antiviral immunity. Given the importance of protein glycosylation for immune function, we investigated the effect that modulation of the highly conserved HLA class I N-glycan has on KIR:HLA interactions and NK cell fu...

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Bibliographic Details
Main Authors: Wilhelm Salzberger, Wilfredo F Garcia-Beltran, Haley Dugan, Supreetha Gubbala, Camille Simoneau, Simon B Gressens, Stephanie Jost, Marcus Altfeld
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4683028?pdf=render