Serum MicroRNAs Reflect Injury Severity in a Large Animal Model of Thoracic Spinal Cord Injury

Abstract Therapeutic development for spinal cord injury is hindered by the difficulty in conducting clinical trials, which to date have relied solely on functional outcome measures for patient enrollment, stratification, and evaluation. Biological biomarkers that accurately classify injury severity...

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Bibliographic Details
Main Authors: Seth Tigchelaar, Femke Streijger, Sunita Sinha, Stephane Flibotte, Neda Manouchehri, Kitty So, Katelyn Shortt, Elena Okon, Michael A. Rizzuto, Ivana Malenica, Amanda Courtright-Lim, Andrew Eisen, Kendall Van Keuren-Jensen, Corey Nislow, Brian K. Kwon
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01299-x