Modeling TGF-β signaling pathway in epithelial-mesenchymal transition

The epithelial-mesenchymal transition (EMT) consists in a morphological change in epithelial cells characterized by the loss of the cell adhesion and the acquisition of mesenchymal phenotype. This process plays a crucial role in the embryonic development and in regulating the tissue homeostasis in t...

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Bibliographic Details
Main Authors: Pasquale Laise, Duccio Fanelli, Pietro Lió, Annarosa Arcangeli
Format: Article
Language:English
Published: AIP Publishing LLC 2012-03-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/1.3697962