Herbal Medicine Containing Licorice May Be Contraindicated for a Patient with an HSD11B2 Mutation

Herbal Medicine Containing Licorice May Be Contraindicated for a Patient with an HSD11B2 Mutation

Licorice ingestion, as well as mutations in the HSD11B2 gene, inhibits 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2) enzyme activity, causing the syndrome of apparent mineral corticoid excess (AME). However, the combined effect of licorice ingestion and an HSD11B2 mutation has never been reporte...

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Bibliographic Details
Main Authors: Indra Sari Kusuma Harahap, Naoko Sasaki, Gunadi, Surini Yusoff, Myeong Jin Lee, Satoru Morikawa, Noriyuki Nishimura, Tomohiro Sasaki, Seiichiro Usuki, Midori Hirai, Mika Ohta, Yutaka Takaoka, Takashi Nishimoto, Hisahide Nishio
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1093/ecam/nep211

Internet

http://dx.doi.org/10.1093/ecam/nep211

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