The latest information on the RIPK1 post-translational modifications and functions

RIPK1 is a protein kinase that simultaneously regulates inflammation, apoptosis, and necroptosis. It is thought that RIPK1 has separate functions through its scaffold structure and kinase domains. Moreover, different post-translational modifications in RIPK1 play distinct or even opposing roles. Und...

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Bibliographic Details
Main Authors: Qiong Wang, Danping Fan, Ya Xia, Qinbin Ye, Xiaoyu Xi, Guoqiang Zhang, Cheng Xiao
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221008659