Cell number in mesenchymal stem cell aggregates dictates cell stiffness and chondrogenesis

Cell number in mesenchymal stem cell aggregates dictates cell stiffness and chondrogenesis

Abstract Background Although mesenchymal stem/stromal cell (MSC) chondrogenic differentiation has been thoroughly investigated, the rudiments for enhancing chondrogenesis have remained largely dependent on external cues. Focus to date has been on extrinsic variables such as soluble signals, culture...

Full description

Bibliographic Details
Main Authors: Melika Sarem, Oliver Otto, Simon Tanaka, V. Prasad Shastri
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Subjects:
Mechanobiology
Caveolin-1
N-cadherin
Survivin
Matrix metalloproteinase-2
Developmental engineering
Online Access:http://link.springer.com/article/10.1186/s13287-018-1103-y

Internet

http://link.springer.com/article/10.1186/s13287-018-1103-y

Similar Items