TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and carries a discouraging prognosis. Its aggressive and highly infiltrative nature renders the current standard treatment of maximal surgical resection, radiation, and chemotherapy relatively ineffective. Identifying the...

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Bibliographic Details
Main Authors: Zonghui Ding, Jean M. Kloss, Serdar Tuncali, Nhan L. Tran, Joseph C. Loftus
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558620301275