Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase.

Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase.

The recombinase RAD51, and its meiosis-specific paralog DMC1 localize at DNA double-strand break (DSB) sites in meiotic prophase. While both proteins are required during meiotic prophase, their spatial organization during meiotic DSB repair is not fully understood. Using super-resolution microscopy...

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Bibliographic Details
Main Authors: Johan A Slotman, Maarten W Paul, Fabrizia Carofiglio, H Martijn de Gruiter, Tessa Vergroesen, Lieke Koornneef, Wiggert A van Cappellen, Adriaan B Houtsmuller, Willy M Baarends
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008595

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https://doi.org/10.1371/journal.pgen.1008595

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