AcuD Gene Knockout Attenuates the Virulence of Talaromyces marneffei in a Zebrafish Model

Talaromyces marneffei is the only dimorphic species in its genus and causes a fatal systemic mycosis named talaromycosis. Our previous study indicated that knockdown of AcuD gene (encodes isocitrate lyase of glyoxylate bypass) of T. marneffei by RNA interference approach attenuated the virulence of...

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Bibliographic Details
Main Authors: Jiao Feng, Zhiwen Chen, Liya He, Xing Xiao, Chunmei Chen, Jieming Chu, Eleftherios Mylonakis, Liyan Xi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-06-01
Series:Mycobiology
Subjects:
Online Access:http://dx.doi.org/10.1080/12298093.2019.1620975