Virtual Screening and Pharmacophore Design for a Novel Theoretical Inhibitor of Macrophage Stimulating Factor as a Metastatic Agent

Introduction: Metastasis is a crucial aspect of cancer. Macrophage stimulating protein (MSP) is a single chain protein and can be cleaved by serum proteases. MSP has several roles in metastasis. In this in silico study, MSP as a metastatic agent was considered as a drug target. Methods: Crystallogra...

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Bibliographic Details
Main Authors: Ibrahim Torktaz, Faezeh Mohamadhashem, Abolghasem Esmaeili, Mohaddeseh Behjati, Sara Sharifzadeh
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2013-09-01
Series:BioImpacts
Subjects:
Online Access:http://dx.doi.org/10.5681/bi.2013.026