Inflammatory Dendritic Cells, Regulated by IL-4 Receptor Alpha Signaling, Control Replication, and Dissemination of Leishmania major in Mice

Inflammatory Dendritic Cells, Regulated by IL-4 Receptor Alpha Signaling, Control Replication, and Dissemination of Leishmania major in Mice

Leishmaniasis is a vector-borne disease caused by Leishmania parasites. Macrophages are considered the primary parasite host cell, but dendritic cells (DCs) play a critical role in initiating adaptive immunity and controlling Leishmania infection. Accordingly, our previous study in CD11ccreIL-4Rα−/l...

Full description

Bibliographic Details
Main Authors: Ramona Hurdayal, Natalie Eva Nieuwenhuizen, Rethabile Khutlang, Frank Brombacher
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Leishmania major
IL-4Rα
IL-4
dendritic cell
mice
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00479/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00479/full

Similar Items