Benchmarking multi-rate codon models.

The single rate codon model of non-synonymous substitution is ubiquitous in phylogenetic modeling. Indeed, the use of a non-synonymous to synonymous substitution rate ratio parameter has facilitated the interpretation of selection pressure on genomes. Although the single rate model has achieved wide...

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Bibliographic Details
Main Authors: Wayne Delport, Konrad Scheffler, Mike B Gravenor, Spencer V Muse, Sergei Kosakovsky Pond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2908124?pdf=render