PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease

PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease

Objective: Increases in hepatic and plasma cholesterol occur in patients with nonalcoholic fatty liver disease (NAFLD), although the reason for this is not well understood. We investigated whether Protease-Activated Receptor 2 (PAR2) plays a role in cholesterol and lipid homeostasis in NAFLD. Method...

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Bibliographic Details
Main Authors: Rajashree Rana, Andrew M. Shearer, Elizabeth K. Fletcher, Nga Nguyen, Srijoy Guha, Daniel H. Cox, Manal Abdelmalek, Ying Wang, James D. Baleja, Lidija Covic, Athan Kuliopulos
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819306982

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http://www.sciencedirect.com/science/article/pii/S2212877819306982

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