Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells.

Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells.

Salt-inducible kinase 1 (SIK1/Snf1lk) belongs to the AMP-activated protein kinase (AMPK) family of kinases, all of which play major roles in regulating metabolism and cell growth. Recent studies have shown that reduced levels of SIK1 are associated with poor outcome in cancers, and that this involve...

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Bibliographic Details
Main Authors: Linn-Karina M Selvik, Shalini Rao, Tonje S Steigedal, Ildri Haltbakk, Kristine Misund, Torunn Bruland, Wenche S Prestvik, Astrid Lægreid, Liv Thommesen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4226541?pdf=render

Internet

http://europepmc.org/articles/PMC4226541?pdf=render

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