Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion
The Roundabout (Robo) guidance receptor family induces axon repulsion in response to its ligand Slit by inducing local cytoskeletal changes; however, the link to the cytoskeleton and the nature of these cytoskeletal changes are poorly understood. Here, we show that the heteropentameric Scar/Wave Reg...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/64474 |