Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion

The Roundabout (Robo) guidance receptor family induces axon repulsion in response to its ligand Slit by inducing local cytoskeletal changes; however, the link to the cytoskeleton and the nature of these cytoskeletal changes are poorly understood. Here, we show that the heteropentameric Scar/Wave Reg...

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Bibliographic Details
Main Authors: Karina Chaudhari, Madhavi Gorla, Chao Chang, Artur Kania, Greg J Bashaw
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/64474