Reciprocal interactions between cancer and Schwann cells contribute to oral cancer progression and pain

Pain associated with oral squamous cell carcinoma (oral SCC) decreases quality of life and survival. The interaction between cancer and the peripheral nerves is known to initiate and amplify pain and contribute to carcinogenesis. Schwann cells envelop peripheral nerves and are activated in response...

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Bibliographic Details
Main Authors: Elizabeth Salvo, Prakaimuk Saraithong, Jared G. Curtin, Malvin N. Janal, Yi Ye
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018362947