Regulatory T cells enhance Th17 migration in psoriatic arthritis which is reversed by anti-TNF
Summary: Regulatory T cells (Treg) prevent the migration of effector T cells toward sites of inflammation, thereby limiting disease progression. We investigated this aspect of Treg function using psoriatic arthritis (PsA) as an exemplar of chronic inflammation. Patients with PsA had an increased Th1...
Main Authors: | Dao X. Nguyen, Helen M. Baldwin, Amara N. Ezeonyeji, Mohammed Rohan Butt, Michael R. Ehrenstein |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422100941X |
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