Regulatory T cells enhance Th17 migration in psoriatic arthritis which is reversed by anti-TNF

Summary: Regulatory T cells (Treg) prevent the migration of effector T cells toward sites of inflammation, thereby limiting disease progression. We investigated this aspect of Treg function using psoriatic arthritis (PsA) as an exemplar of chronic inflammation. Patients with PsA had an increased Th1...

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Bibliographic Details
Main Authors: Dao X. Nguyen, Helen M. Baldwin, Amara N. Ezeonyeji, Mohammed Rohan Butt, Michael R. Ehrenstein
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422100941X