G protein-coupled receptor kinase 5 mediates Tazarotene-induced gene 1-induced growth suppression of human colon cancer cells

<p>Abstract</p> <p>Background</p> <p>Tazarotene-induced gene 1 (TIG1) is a retinoid-inducible type II tumour suppressor gene. The B isoform of TIG1 (TIG1B) inhibits growth and invasion of cancer cells. Expression of TIG1B is frequently downregulated in various cancer ti...

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Bibliographic Details
Main Authors: Wang Chun-Hua, Tsai Ya-Ming, Shyu Rong-Yaun, Tsai Fu-Ming, Wu Chang-Chieh, Jiang Shun-Yuan
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/11/175