Preclinical Studies of the Biosafety and Efficacy of Human Bone Marrow Mesenchymal Stem Cells Pre-Seeded into β-TCP Scaffolds after Transplantation

Preclinical Studies of the Biosafety and Efficacy of Human Bone Marrow Mesenchymal Stem Cells Pre-Seeded into β-TCP Scaffolds after Transplantation

Background: Cell-Based Therapies (CBT) constitute a valid procedure for increasing the quantity and quality of bone in areas with an inadequate bone volume. However, safety and efficacy should be investigated prior to clinical application. The objective of this study was to evaluate the biodistribut...

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Bibliographic Details
Main Authors: Mar Gonzálvez-García, Carlos M. Martinez, Victor Villanueva, Ana García-Hernández, Miguel Blanquer, Luis Meseguer-Olmo, Ricardo E. Oñate Sánchez, José M. Moraleda, Francisco Javier Rodríguez-Lozano
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Materials
Subjects:
preclinical biosafety
bone substitute
mesenchymal stem cells
β-tricalcium phosphate
tissue engineering
Online Access:http://www.mdpi.com/1996-1944/11/8/1349

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http://www.mdpi.com/1996-1944/11/8/1349

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