Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a <i>COMMD1</i>-Deficient Dog Model of Metabolic Liver Disease

Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a <i>COMMD1</i>-Deficient Dog Model of Metabolic Liver Disease

The shortage of liver organ donors is increasing and the need for viable alternatives is urgent. Liver cell (hepatocyte) transplantation may be a less invasive treatment compared with liver transplantation. Unfortunately, hepatocytes cannot be expanded in vitro, and allogenic cell transplantation re...

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Bibliographic Details
Main Authors: Hedwig S. Kruitwagen, Loes A. Oosterhoff, Monique E. van Wolferen, Chen Chen, Sathidpak Nantasanti Assawarachan, Kerstin Schneeberger, Anne Kummeling, Giora van Straten, Ies C. Akkerdaas, Christel R. Vinke, Frank G. van Steenbeek, Leonie W.L. van Bruggen, Jeannette Wolfswinkel, Guy C.M. Grinwis, Sabine A. Fuchs, Helmuth Gehart, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
dog
copper
organoids
transplantation
autologous
hepatocytes
cell transplantation
wilson’s disease
Online Access:https://www.mdpi.com/2073-4409/9/2/410

Internet

https://www.mdpi.com/2073-4409/9/2/410

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