Construction and analysis of a modular model of caspase activation in apoptosis

<p>Abstract</p> <p>Background</p> <p>A key physiological mechanism employed by multicellular organisms is apoptosis, or programmed cell death. Apoptosis is triggered by the activation of caspases in response to both extracellular (extrinsic) and intracellular (intrinsic...

Full description

Bibliographic Details
Main Authors: Ho Kenneth L, Harrington Heather A, Ghosh Samik, Tung KC
Format: Article
Language:English
Published: BMC 2008-12-01
Series:Theoretical Biology and Medical Modelling
Online Access:http://www.tbiomed.com/content/5/1/26