An integrated gene regulatory network controls stem cell proliferation in teeth.

Epithelial stem cells reside in specific niches that regulate their self-renewal and differentiation, and are responsible for the continuous regeneration of tissues such as hair, skin, and gut. Although the regenerative potential of mammalian teeth is limited, mouse incisors grow continuously throug...

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Bibliographic Details
Main Authors: Xiu-Ping Wang, Marika Suomalainen, Szabolcs Felszeghy, Laura C Zelarayan, Maria T Alonso, Maksim V Plikus, Richard L Maas, Cheng-Ming Chuong, Thomas Schimmang, Irma Thesleff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0050159