A MiSeq-HyDRA platform for enhanced HIV drug resistance genotyping and surveillance

A MiSeq-HyDRA platform for enhanced HIV drug resistance genotyping and surveillance

Abstract Conventional HIV drug resistance (HIVDR) genotyping utilizes Sanger sequencing (SS) methods, which are limited by low data throughput and the inability of detecting low abundant drug resistant variants (LADRVs). Here we present a next generation sequencing (NGS)-based HIVDR typing platform...

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Bibliographic Details
Main Authors: Tracy Taylor, Emma R. Lee, Mikaela Nykoluk, Eric Enns, Binhua Liang, Rupert Capina, Marie-Krystel Gauthier, Gary Van Domselaar, Paul Sandstrom, James Brooks, Hezhao Ji
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-45328-3

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https://doi.org/10.1038/s41598-019-45328-3

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