Continuous Exposure to Non-Soluble β-Glucans Induces Trained Immunity in M-CSF-Differentiated Macrophages

Continuous Exposure to Non-Soluble β-Glucans Induces Trained Immunity in M-CSF-Differentiated Macrophages

Beta-glucans enable functional reprogramming of innate immune cells, a process defined as “trained immunity”, which results in enhanced host responsiveness against primary (training) and/or secondary infections (resilience). Trained immunity holds great promise for promoting immune responses in grou...

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Bibliographic Details
Main Authors: Bart G. J. Moerings, Priscilla de Graaff, Matthew Furber, Renger F. Witkamp, Reno Debets, Jurriaan J. Mes, Jeroen van Bergenhenegouwen, Coen Govers
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
β-glucan
trained immunity
macrophage model
resilience
dectin-1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.672796/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.672796/full

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