Genetic polymorphisms of inflammasome genes associated with pediatric acute lymphoblastic leukemia and clinical prognosis in the Brazilian Amazon

Genetic polymorphisms of inflammasome genes associated with pediatric acute lymphoblastic leukemia and clinical prognosis in the Brazilian Amazon

Abstract The immune system plays an important role in the control of cancer development. To investigate the possible association of inflammasome genes to childhood leukemia we performed a case-control study with 158 patients with acute lymphoblastic leukemia and 192 healthy individuals. The IL1B and...

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Bibliographic Details
Main Authors: Fabíola Silva Alves, Lilyane Amorim Xabregas, Marlon Wendell Athaydes Kerr, Gláucia Lima Souza, Daniele Sá Pereira, Fábio Magalhães-Gama, Mirian Rodrigues Ribeiro Santiago, Nadja Pinto Garcia, Andréa Monteiro Tarragô, Maurício Morishi Ogusku, Aya Sadahiro, Adriana Malheiro, Allyson Guimarães Costa
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89310-4

Internet

https://doi.org/10.1038/s41598-021-89310-4

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