Improving ancient DNA read mapping against modern reference genomes

<p>Abstract</p> <p>Background</p> <p>Next-Generation Sequencing has revolutionized our approach to ancient DNA (aDNA) research, by providing complete genomic sequences of ancient individuals and extinct species. However, the recovery of genetic material from long-dead o...

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Bibliographic Details
Main Authors: Schubert Mikkel, Ginolhac Aurelien, Lindgreen Stinus, Thompson John F, AL-Rasheid Khaled AS, Willerslev Eske, Krogh Anders, Orlando Ludovic
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/13/178