Leishmania donovani infection suppresses Allograft Inflammatory Factor-1 in monocytes and macrophages to inhibit inflammatory responses

Leishmania donovani infection suppresses Allograft Inflammatory Factor-1 in monocytes and macrophages to inhibit inflammatory responses

Abstract Macrophages and monocytes are important for clearance of Leishmania infections. However, immune evasion tactics employed by the parasite results in suppressed inflammatory responses, marked by deficient macrophage functions and increased accumulation of monocytes. This results in an ineffec...

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Bibliographic Details
Main Authors: Ricardo Louzada da Silva, Diana M. Elizondo, Nailah Z. D. Brandy, Naomi L. Haddock, Thomas A. Boddie, Laís Lima de Oliveira, Amélia Ribeiro de Jesus, Roque Pacheco de Almeida, Tatiana Rodrigues de Moura, Michael W. Lipscomb
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79068-6

Internet

https://doi.org/10.1038/s41598-020-79068-6

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