Synaptically-competent neurons derived from canine embryonic stem cells by lineage selection with EGF and Noggin.

Pluripotent stem cell lines have been generated in several domestic animal species; however, these lines traditionally show poor self-renewal and differentiation. Using canine embryonic stem cell (cESC) lines previously shown to have sufficient self-renewal capacity and potency, we generated and com...

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Bibliographic Details
Main Authors: Jared T Wilcox, Jonathan K Y Lai, Esther Semple, Brigitte A Brisson, Cathy Gartley, John N Armstrong, Dean H Betts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3096636?pdf=render