Differential toxicities of triptolide to immortalized podocytes and the podocytes in vivo

Differential toxicities of triptolide to immortalized podocytes and the podocytes in vivo

Triptolide (TP) has an anti-proteinuric effect and is used for the treatment of podocytopathies. TP has also been shown to act directly on immortalized podocytes in culture to protect them from injury. In the present study, we examined the effect of TP on healthy podocytes both in vitro and in vivo...

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Bibliographic Details
Main Authors: Mengjie Sun, Hui Song, Yuting Ye, Qianqian Yang, Xiaodong Xu, Xiaodong Zhu, Jiong Zhang, Shaolin Shi, Jinquan Wang, Zhihong Liu
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Triptolide toxicity
Podocyte injury
Immortalized podocyte
Apoptosis
Glucocorticoid
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218363315

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http://www.sciencedirect.com/science/article/pii/S0753332218363315

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