A new insight in chimeric antigen receptor-engineered T cells for cancer immunotherapy

Abstract Adoptive cell therapy using chimeric antigen receptor (CAR)-engineered T cells has emerged as a very promising approach to combating cancer. Despite its ability to eliminate tumors shown in some clinical trials, CAR-T cell therapy involves some significant safety challenges, such as cytokin...

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Bibliographic Details
Main Authors: Erhao Zhang, Hanmei Xu
Format: Article
Language:English
Published: BMC 2017-01-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13045-016-0379-6