lncDIFF: a novel quasi-likelihood method for differential expression analysis of non-coding RNA

Abstract Background Long non-coding RNA (lncRNA) expression data have been increasingly used in finding diagnostic and prognostic biomarkers in cancer studies. Existing differential analysis tools for RNA sequencing do not effectively accommodate low abundant genes, as commonly observed in lncRNAs....

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Bibliographic Details
Main Authors: Qian Li, Xiaoqing Yu, Ritu Chaudhary, Robbert J. C. Slebos, Christine H. Chung, Xuefeng Wang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-019-5926-4