Coupling Peptide Antigens to Virus-Like Particles or to Protein Carriers Influences the Th1/Th2 Polarity of the Resulting Immune Response

Coupling Peptide Antigens to Virus-Like Particles or to Protein Carriers Influences the Th1/Th2 Polarity of the Resulting Immune Response

We have conjugated the S9 peptide, a mimic of the group B streptococcal type III capsular polysaccharide, to different carriers in an effort to elicit an optimal immune response. As carriers, we utilized the soluble protein keyhole limpet hemocyanin and virus-like particles (VLPs) from two plant vir...

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Bibliographic Details
Main Authors: Rattanaruji Pomwised, Uraiwan Intamaso, Martin Teintze, Mark Young, Seth H. Pincus
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Vaccines
Subjects:
group B streptococcus
Streptococcus agalactiae
capsular polysaccharide
antigen
mimotope
synthetic peptide
Online Access:http://www.mdpi.com/2076-393X/4/2/15

Internet

http://www.mdpi.com/2076-393X/4/2/15

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