In Vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer’s Aβ protein
Amyloid β (Aβ) is the major constituent of the brain deposits found in parenchymal plaques and cerebral blood vessels of patients with Alzheimer’s disease (AD). Several lines of investigation support the notion that synaptic pathology, one of the strongest correlates to cognitive impairment, is rela...
Main Authors: | Farron Lynn McIntee, Patrizia Giannoni, Steven Blais, George Sommer, Thomas Neubert, Agueda Rostagno, Jorge Ghiso |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-09-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00223/full |
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