Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.

Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.

Natural Killer (NK) cells are innate immune cells that secrete lytic granules to directly kill virus-infected or transformed cells across an immune synapse. However, a major gap in understanding this process is in establishing how lytic granules pass through the mesh of cortical actin known to under...

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Bibliographic Details
Main Authors: Alice C N Brown, Stephane Oddos, Ian M Dobbie, Juha-Matti Alakoskela, Richard M Parton, Philipp Eissmann, Mark A A Neil, Christopher Dunsby, Paul M W French, Ilan Davis, Daniel M Davis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21931537/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21931537/?tool=EBI

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