Extracellular Vesicle-Encapsulated miR-29b-3p Released From Bone Marrow-Derived Mesenchymal Stem Cells Underpins Osteogenic Differentiation

Extracellular Vesicle-Encapsulated miR-29b-3p Released From Bone Marrow-Derived Mesenchymal Stem Cells Underpins Osteogenic Differentiation

ObjectiveMesenchymal stem cells (MSCs) confer therapeutic benefits in various pathologies and cancers by releasing extracellular vesicles (EVs) loaded with bioactive compounds. Herein, we identified bone marrow MSC (BMSC)-derived EVs harboring microRNA (miR)-29b-3p to regulate osteogenic differentia...

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Bibliographic Details
Main Authors: Xueliang Zhang, Wenji Wang, Yongping Wang, Haiyan Zhao, Xingwen Han, Tong Zhao, Peng Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
microRNA-29b-3p
KDM5A
SOCS1
NF-κB
extracellular vesicles
osteogenic differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.581545/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.581545/full

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