Mannan detecting C-type lectin receptor probes recognise immune epitopes with diverse chemical, spatial and phylogenetic heterogeneity in fungal cell walls.

During the course of fungal infection, pathogen recognition by the innate immune system is critical to initiate efficient protective immune responses. The primary event that triggers immune responses is the binding of Pattern Recognition Receptors (PRRs), which are expressed at the surface of host i...

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Bibliographic Details
Main Authors: Ingrida Vendele, Janet A Willment, Lisete M Silva, Angelina S Palma, Wengang Chai, Yan Liu, Ten Feizi, Maria Spyrou, Mark H T Stappers, Gordon D Brown, Neil A R Gow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007927