PCR-activated cell sorting for cultivation-free enrichment and sequencing of rare microbes.

Microbial systems often exhibit staggering diversity, making the study of rare, interesting species challenging. For example, metagenomic analyses of mixed-cell populations are often dominated by the sequences of the most abundant organisms, while those of rare microbes are detected only at low leve...

Full description

Bibliographic Details
Main Authors: Shaun W Lim, Tuan M Tran, Adam R Abate
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4309575?pdf=render