The Differential Effects of Leukocyte-Containing and Pure Platelet-Rich Plasma on Nucleus Pulposus-Derived Mesenchymal Stem Cells: Implications for the Clinical Treatment of Intervertebral Disc Degeneration

Background. Platelet-rich plasma (PRP) is a promising strategy for intervertebral disc degeneration. However, the potential harmful effects of leukocytes in PRP on nucleus pulposus-derived mesenchymal stem cells (NPMSCs) have seldom been studied. This study aimed at comparatively evaluating effects...

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Bibliographic Details
Main Authors: Jun Jia, Shan-zheng Wang, Liang-yu Ma, Jia-bin Yu, Yu-dong Guo, Chen Wang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2018/7162084