Synchrotron-based infrared spectroscopy brings to light the structure of protein aggregates in neurodegenerative diseases
The accumulation of misfolded proteins in the form of aggregates characterizes a number of diseases of the central nervous system such as Alzheimer’s disease, Parkinson’s disease, prion diseases, and the diseases of polyglutamine expansion. Recent evidence obtained in vitro and in mice has suggested...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2014-12-01
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Series: | Reviews in Analytical Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.1515/revac-2014-0016 |