In situ Gelling Amphotericin B Nanofibers: A New Option for the Treatment of Keratomycosis

In situ Gelling Amphotericin B Nanofibers: A New Option for the Treatment of Keratomycosis

The purpose of our research was the development of Amphotericin B-loaded in situ gelling nanofibers for the treatment of keratomycosis. Different formulation strategies were applied to increase the drug load of the sparingly water-soluble Amphotericin B in electrospun Gellan Gum/Pullulan fibers. The...

Full description

Bibliographic Details
Main Authors: Benedikt Göttel, Henrike Lucas, Frank Syrowatka, Wolfgang Knolle, Judith Kuntsche, Joana Heinzelmann, Arne Viestenz, Karsten Mäder
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
keratomycosis
electrospinning
amphotericin B
polyelectrolyte complex
PLGA nanoparticle
in situ forming
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.600384/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2020.600384/full

Similar Items