Long non-coding RNA MCM3AP-AS1 protects chondrocytes ATDC5 and CHON-001 from IL-1β-induced inflammation via regulating miR-138-5p/SIRT1

Long non-coding RNA MCM3AP-AS1 protects chondrocytes ATDC5 and CHON-001 from IL-1β-induced inflammation via regulating miR-138-5p/SIRT1

Osteoarthritis (OA) is a chronic inflammatory joint disease. Increased apoptosis of chondrocytes contributes to cartilage degradation in OA pathogenesis. The function of lncRNA MCM3AP-AS1 in regulating the viability of chondrocytes still awaits further elaboration. In this work, MCM3AP-AS1, miR-138-...

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Bibliographic Details
Main Authors: Jianming Shi, Fuyang Cao, Yingjian Chang, Chaofei Xin, Xu Jiang, Jianzhong Xu, Shitao Lu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
mcm3ap-as1
mir-138-5p
sirt1
osteoarthritis
Online Access:http://dx.doi.org/10.1080/21655979.2021.1905247

Internet

http://dx.doi.org/10.1080/21655979.2021.1905247

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